Application

Western Blot Analysis: 1 µg/mL from a representative lot detected ID4 on 10 µg of mouse lymph node tissue lysate.

Use Anti-ID4 Antibody, clone DML07 (Mouse Monoclonal Antibody) validated in WB to detect ID4 also known as DNA-binding protein inhibitor ID-4, Class B basic helix-loop-helix protein 27, bHLHb27.

General description

ID4 is an inhibitor of differentiation protein, which, along with ID1, ID2 and ID3, plays a key role in the regulation of lineage commitment, cell fate decisions and in the timing of differentiation during neurogenesis, lymphopoiesis and neovascularisation (angiogenesis). ID proteins, induced by the bone morphogenic protein-SMAD pathway, have also been shown to cooperate with LIF to ensure that embryonic stem cells opt for self-renewal.

Immunogen

KLH-conjugated linear peptide corresponding to human ID4.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Quality

Evaluated by Western Blot in human lung tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected ID4 on 10 µg of human lung tissue lysate.

Target description

~17 kDa observed